Genetic analysis of gastric cancer with distinctive family history

Gastric cancer and family history

Gastric cancer is associated with high morbidity and mortality rates worldwide. Identifying individuals at high risk is important for surveillance and prevention of gastric cancer. Having first-degree relatives diagnosed with gastric cancer is a strong and consistent risk factor for gastric cancer, but the pathogenic mechanisms behind this familial aggregation are unclear. Against this backgrou...

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risk of gastric cancer associated with family history of other cancers of the digestive system

introduction: the objective of the present study is to investigate the relationship between the familial history of digestive system cancers and development of gastric cancer. methods: in this case-control study conducted in 2012, 84 patients with a definite diagnosis of gastric cancer, diagnosed using endoscopy and pathological study of biopsies, were compared with 84 people with the same age ...

Clinicopathological Features and Survival of Patients with Gastric Cancer with a Family History: a Large Analysis of 2,736 Patients with Gastric Cancer

PURPOSE Previous studies indicated conflicting results regarding the prognosis of gastric cancer with a family history (FHX). This study aimed to determine the clinicopathological features and survival of patients with gastric cancer with a FHX. MATERIALS AND METHODS We reviewed 2,736 patients with gastric cancer who underwent surgery between 2003 and 2009. The prognostic value of a FHX was d...

family history of colorectal cancer in iran

introduction and aims: previous reports show a high proportion of young crc patients in iran. in this study we aim to look for the clustering of colorectal cancer in families of a series of crc patients from iran. materials and methods: the family history of cancer is traced in 449 crc patients of which 112 were 45 years or younger and 337 were older than 45years at time of diagnosis. the patie...